GammaTile Therapy


Learn more about GammaTile Therapy

We invite you to browse through the videos, read the FAQs, and take a deep dive into the science behind GammaTile Therapy by watching the webinars and reading the clinical publications.

Note: In January 2020, GammaTile Therapy was FDA cleared for the treatment of newly diagnosed malignant brain tumors of all types in addition to the existing clearance for recurrent brain tumors. 

GammaTile in the Media

WeTV | March 21, 2020 | New approach for the treatment of brain tumors on the lifestyle list

North Carolina CBS | January 24, 2020 | Vidant Health™ and the ECU Brody School of Medicine successfully perform the first-in-state GammaTile procedure

Cronkite News Division of Arizona PBS | Oct 22, 2019 | Battling brain tumors with time-released radiation

Arizona CBS | August 14, 2019 | New therapy to slow down brain tumors forever changes Arizona woman's life

Florida NBC | March 20, 2020 | GammaTile: New approach for the treatment of brain tumors

Ohio CBS | November 7, 2019 | New brain cancer therapy provides radiation right at site of tumor 

Ohio CBS | August 20, 2019 | Mayfield Brain and Spine neurosurgeon using new radiation therapy

Arizona PBS | June 11, 2019 | GammaTile Therapy implantable brain tumor treatment with Dr David Brachman 

Minnesota CBS | February 14, 2019 | New brain cancer treatment GammaTile Therapy at University of Minnesota with survivor Linda Tinega


March 18, 2020 | Physician Perspective on GammaTile Therapy | Dr. McCracken, a neurosurgeon at Piedmont Atlanta Hospital

August 14, 2019 | Physician Perspective on GammaTile Therapy | Dr Clark Chen, a neurosurgeon at University of Minnesota Health

Physician Perspectives


Founder Interview | October 1, 2018 |
Introducing GammaTile Therapy

What I like about GammaTile is that they’re taking a radiation technology that already exists and making it safer and easier to deliver… [It] should be equally effective and faster to implant after tumor surgery…[It’s] better for patients (with less anesthesia time) and safer for the staff (with less exposure in the OR).

  Dr Helen Shih  

Radiation Oncologist at Massachusetts General Hospital


Below are the answers to important questions about GammaTile Therapy. Speak with your treatment team to see if GammaTile Therapy is right for you or your loved one.




American Brain Tumor Association | February 27, 2020

Webinar: Therapies Given During Surgery 

This webinar provides a detailed overview of surgically implanted brain tumor therapies, including GammaTile Surgically Targeted Radiation Therapy (STaRT). Dr John A. Boockvar, the director of the Brain Tumor and Pituitary/Neuroendocrine Center at Lenox Hill, discusses various treatment options, highlights their differences, and provides guidance on how patients can talk with their heath team about their care plan.

2019 Brain Tumor Webinar Series | May 26, 2019

Webinar: GammaTiles for Brain Tumors

Watch an in-depth educational webinar about GammaTile Therapy, presented by world-renowned neurosurgeon Dr Joseph Zabramski and hosted by The Musella Foundation. Content includes background, safety and efficacy, surgical placement, a case study, and clinical trial information.

Clinical Publications

Evolving strategies to potentially further optimize surgical interventions in brain cancer 

Bindi B. Parikh, MD and Elizabeth C. Neil, MD, in Current Oncology Reports. 2020; 22, 32. Read here

Resection and permanent intracranial brachytherapy using modular, biocompatible cesium-131 implants: results in 20 recurrent, previously irradiated meningiomas

David G. Brachman, MD, Emad Youssef, MD, Christopher J. Dardis, MD, Nader Sanai, MD, Joseph M. Zabramski, MD, Kris A. Smith, MD, Andrew S. Little, MD, Andrew G. Shetter, MD, Theresa Thomas, MS, Heyoung L. McBride, MD, MS, Stephen Sorensen, PhD, Robert F. Spetzler, MD, and Peter Nakaji, MDl, in the Journal of Neurosurgery. 2018;131:1683-1994. 
Read here

Surgically targeted radiation therapy: a prospective trial in 79 recurrent, previously irradiated intracranial neoplasms on a prospective clinical trial

Peter Nakaji, MD, FAANS; Emad Youssef, MD; Christopher Dardis, MD; Kris Smith, MD; Dilini Pinnaduwage, PhD; David Brachman, MD, at the 2019 AANS Meeting. Read here

Surgically targeted radiation therapy: safety profile of collagen tile brachytherapy in 79 recurrent, previously irradiated intracranial neoplasms on a prospective clinical trial.

David Brachman, MD, Emad Youssef, MD, Christopher Dardis, MD, Kris Smith, MD, Dilini Pinnaduwage, PhD, Peter Nakaji, MD, in Brachytherapy. 2019;18(3):S35-S36. doi: 10.1016/j.brachy.2019.04.076. Read here


RTHP-32. First experience with GammaTile permanent implants for recurrent brain tumors

Clara Ferreira, Parham Alaei, Clark Chen, Margaret Reynolds, David Sterling, Kathryn Dusenbery, in Neuro-Oncology. 2019;21 (Supplement_6):vi216. doi:10.1093/neuonc/noz175.903. Read here


  1. Nakaji P, Youssef E, Dardis C, Smith K, Pinnaduwage D, Brachman D. Surgically targeted radiation therapy: a prospective trial in 79 recurrent, previously irradiated intracranial neoplasms. Poster presented at: 2019 AANS Annual Scientific Meeting; April 2019; San Diego, CA. 

  2. Brachman D, Youssef E, Dardis C, Smith K, Pinnaduwage D, Nakaji P. Surgically targeted radiation therapy: Safety profile of collagen tile brachytherapy in 79 recurrent, previously irradiated intracranial neoplasms on a prospective clinical trial. Brachytherapy. 2019;18(3):S35-S36.



GammaTile Therapy is intended to deliver radiation therapy in patients with newly diagnosed malignant brain tumors and recurrent brain tumors. The potential for, and symptoms of, adverse events related to radiation exposure vary depending on the radiosensitivity of the exposed tissue, the amount of radiation delivered, and the placement of GammaTile(s). Serious side effects related to GammaTile Therapy are rare, and may include radiation brain changes including necrosis. GammaTile Therapy should not be used for patients with known history of hypersensitivity to bovine-derived materials. Possible complications can occur with any neurosurgical procedure, including cerebrospinal fluid leaks, infection, delayed hemorrhage, and adhesion formation.

  • Twitter
  • LinkedIn
  • Facebook
  • YouTube

©2020 GT Medical Technologies, Inc. I All rights reserved